4-Amino-5-fluoropyridin-2(1H)-one

Base Information

Chemical Name:4-Amino-5-fluoropyridin-2(1H)-one
CAS No.:105252-98-0
Molecular Formula:C₅H₅FN₂O
Molecular Weight:128.106
Hs Code.:
ChEMBL ID:CHEMBL116923
DSSTox Substance ID:DTXSID201300548
Nikkaji Number:J1.332.125F
Mol file:105252-98-0.mol

Synonyms:105252-98-0;4-Amino-5-fluoropyridin-2(1H)-one;4-Amino-5-fluoro-1H-pyridin-2-one;2(1H)-Pyridinone,4-amino-5-fluoro-(9CI);CHEMBL116923;SCHEMBL1687042;DTXSID201300548;MFCD19204946;4-Amino-5-fluoro-2(1H)-pyridinone;AKOS006341811;SB13503;SY343691;G61323

Suppliers and Price of 4-Amino-5-fluoropyridin-2(1H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
4-Amino-5-fluoro-2-hydroxypyridine
250mg
$ 666.40

Total 4 raw suppliers

Chemical Property of 4-Amino-5-fluoropyridin-2(1H)-one

Chemical Property:

PSA：58.88000
LogP:0.67740
XLogP3:-0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:128.03859095
Heavy Atom Count:9
Complexity:207

Purity/Quality:

97% ^*data from raw suppliers

4-Amino-5-fluoro-2-hydroxypyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CNC1=O)F)N

Technology Process of 4-Amino-5-fluoropyridin-2(1H)-one

There total 3 articles about 4-Amino-5-fluoropyridin-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 105252-93-5
4-amino-3,5,6-trifluoro-2(1H)-pyridinone

: 105252-98-0
5-flucytosine

: 105252-97-9
3-fluoro-3-deazacytosine

Guidance literature:: With hydrazine; In ethanol; for 72h; Heating;
DOI:10.1021/jm00385a016

Reference yield:

: 1682-20-8
2,3,5,6-tetrafluoropyridin-4-amine

: 105252-98-0
5-flucytosine

Guidance literature:: Multi-step reaction with 2 steps

1: 73.7 percent / 1N aq. NaOH / 6 h / Heating

2: 8 percent / H₂NNH₂ / ethanol / 72 h / Heating

With sodium hydroxide; hydrazine; In ethanol;
DOI:10.1021/jm00385a016