3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester

Base Information

• Chemical Name: 3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester
• CAS No.: 197655-19-9
• Molecular Formula: C₁₃H₁₇N₃O₃
• Molecular Weight: 263.296
• Mol file: 197655-19-9.mol

Synonyms:3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester

Chemical Property of 3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester

There total 1 articles about 3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

p-toluic hydrazide (3619-22-5) + ethyl 3-amino-3-ethoxypropenoate (39632-87-6) → 3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester (197655-19-9)

Guidance literature:

In ethanol; at 70 ℃; for 0.0833333h;

DOI:10.1002/jhet.5570340432

Reference yield: 92.0%

1,1,1-trifluoro-4-methoxypent-3-en-2-one (135351-20-1,102145-82-4) + 3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester (197655-19-9) → 4-Methyl-2-[N'-(4-methyl-benzoyl)-hydrazino]-6-trifluoromethyl-nicotinic acid ethyl ester

Guidance literature:

With potassium carbonate; In dimethyl sulfoxide; for 1h; Ambient temperature;

DOI:10.1002/jhet.5570340432

Reference yield: 53.0%

1,1,1-trifluoro-4-methoxypent-3-en-2-one (135351-20-1,102145-82-4) + 3-Amino-3-[(4-methyl-benzoyl)-hydrazono]-propionic acid ethyl ester (197655-19-9) → 6-Methyl-2-[N'-(4-methyl-benzoyl)-hydrazino]-4-trifluoromethyl-nicotinic acid ethyl ester + 4-Methyl-2-[N'-(4-methyl-benzoyl)-hydrazino]-6-trifluoromethyl-nicotinic acid ethyl ester

Guidance literature:

In ethanol; for 2h; Heating;

DOI:10.1002/jhet.5570340432

upstream raw materials:

p-toluic hydrazide

ethyl 3-amino-3-ethoxypropenoate