4-(8-Chloro-4H-imidazo[2,1-c][1,4]benzoxazin-2-yl)phenyl methyl ether

Base Information

• Chemical Name: 4-(8-Chloro-4H-imidazo[2,1-c][1,4]benzoxazin-2-yl)phenyl methyl ether
• CAS No.: 104971-84-8
• Molecular Formula: C₁₇H₁₃ClN₂O₂
• Molecular Weight: 312.755
• Hs Code.: 2934999090
• Mol file: 104971-84-8.mol

Synonyms:4-(8-Chloro-4H-imidazo[2,1-c][1,4]benzoxazin-2-yl)phenyl methyl ether

Chemical Property of 4-(8-Chloro-4H-imidazo[2,1-c][1,4]benzoxazin-2-yl)phenyl methyl ether

Chemical Property:

• PSA: 36.28000
• LogP: 4.09370

Purity/Quality:

4-(8-CHLORO-4H-IMIDAZO-[2,1-C][1,4]-BENZOXAZIN-2-YL)PHENYL METHYL ETHER 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-(8-Chloro-4H-imidazo[2,1-c][1,4]benzoxazin-2-yl)phenyl methyl ether

There total 3 articles about 4-(8-Chloro-4H-imidazo[2,1-c][1,4]benzoxazin-2-yl)phenyl methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

6-Chloro-4-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-4H-benzo[1,4]oxazin-3-one (105492-51-1) → 8-Chloro-2-(4-methoxy-phenyl)-4H-5-oxa-3,9b-diaza-cyclopenta[a]naphthalene (104971-84-8)

Guidance literature:

With ammonium acetate; acetic acid; for 4h; Heating;

Reference yield:

6-chloro-2H-1,4-benzoxazin-3(4H)-one (7652-29-1) → 8-Chloro-2-(4-methoxy-phenyl)-4H-5-oxa-3,9b-diaza-cyclopenta[a]naphthalene (104971-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / potassium carbonate / acetone / 5 h / Heating

2: 73 percent / ammonium acetate, glacial acetic acid / 4 h / Heating

With ammonium acetate; potassium carbonate; acetic acid; In acetone;

Reference yield:

2-Bromo-4'-methoxyacetophenone (2632-13-5) → 8-Chloro-2-(4-methoxy-phenyl)-4H-5-oxa-3,9b-diaza-cyclopenta[a]naphthalene (104971-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / potassium carbonate / acetone / 5 h / Heating

2: 73 percent / ammonium acetate, glacial acetic acid / 4 h / Heating

With ammonium acetate; potassium carbonate; acetic acid; In acetone;

upstream raw materials:

6-Chloro-4-[2-(4-methoxy-phenyl)-2-oxo-ethyl]-4H-benzo[1,4]oxazin-3-one

6-chloro-2H-1,4-benzoxazin-3(4H)-one

2-Bromo-4'-methoxyacetophenone