trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester

Base Information

• Chemical Name: trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester
• CAS No.: 738608-39-4
• Molecular Formula: C₂₀H₁₄F₃NO₃S
• Molecular Weight: 405.397
• Mol file: 738608-39-4.mol

Synonyms:trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester

Chemical Property of trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester

There total 1 articles about trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-hydroxy-2-methyl-1-phenyl-9H-carbazole (123719-47-1) + trifluoroacetic anhydride (407-25-0) → trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester (738608-39-4)

Guidance literature:

With 2,6-dimethylpyridine; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2004.05.053

Reference yield: 86.0%

trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester (738608-39-4) → 2-methyl-1-phenyl-9H-carbazole (106103-38-2)

Guidance literature:

With formic acid; triethylamine; triphenylphosphine; palladium diacetate; In N,N-dimethyl-formamide; at 80 ℃; for 24h;

DOI:10.1016/j.tetlet.2004.05.053

Reference yield:

trifluoro-methanesulfonic acid 2-methyl-1-phenyl-9H-carbazol-3-yl ester (738608-39-4) → 2-methyl-1-phenyl-3-trimethylsilanylethynyl-9H-carbazole

Guidance literature:

Multi-step reaction with 2 steps

1: 86 percent / PPh₃; Et₃N; HCO₂H / Pd(OAc)2 / dimethylformamide / 24 h / 80 °C

2: 87 percent / CuI; Et₃N / bis(triphenylphosphine)palladium dichloride / dimethylformamide / 20 h / 90 °C

With copper(l) iodide; formic acid; triethylamine; triphenylphosphine; bis-triphenylphosphine-palladium(II) chloride; palladium diacetate; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2004.05.053

upstream raw materials:

3-hydroxy-2-methyl-1-phenyl-9H-carbazole

trifluoroacetic anhydride

Downstream raw materials:

2-methyl-1-phenyl-9H-carbazole