α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile

Base Information

Chemical Name:α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile
CAS No.:116078-78-5
Molecular Formula:C₂₈H₃₃N₃
Molecular Weight:411.59
Hs Code.:

Synonyms:α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile

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Chemical Property of α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile

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Technology Process of α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile

There total 1 articles about α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4377-33-7
2-chloromethylpyridine

: 91257-05-5
α-[2-[bis(1-methylethyl)amino]ethyl]-4-phenylphenylacetonitrile

: 116078-78-5
α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile

Guidance literature:: With potassium hydride; In toluene; at 65 - 70 ℃; for 1h;
DOI:10.1021/jm00119a017

Reference yield:

: 116078-78-5
α-[2-[bis(1-methylethyl)amino]ethyl]-α-(4-phenylphenyl)-2-pyridinepropanenitrile

: 2-[2-[bis(1-methylethyl)amino]ethyl]-2-(4-phenylphenyl)hexahydro-3(2H)-indolizinone

Guidance literature:: Multi-step reaction with 2 steps

1: 48 percent / KOH / 2-methyl-propan-2-ol / Heating

2: 64 percent / conc. HCl, hydrogen / PtO₂ / ethanol / 24 h / 2585.7 Torr / Ambient temperature

With hydrogenchloride; potassium hydroxide; hydrogen; platinum(IV) oxide; In ethanol; tert-butyl alcohol;
DOI:10.1021/jm00119a017