(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate

Base Information

Chemical Name:(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate
CAS No.:1257420-17-9
Molecular Formula:C₂₂H₃₄O₃
Molecular Weight:346.51
Hs Code.:

Synonyms:(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate

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Chemical Property of (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate

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Technology Process of (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate

There total 1 articles about (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1223562-83-1
(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (4-ethylphenyl)(oxo)acetate

: 557-20-0
diethylzinc

: 1257420-17-9
(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate

Guidance literature:: (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (4-ethylphenyl)(oxo)acetate; With zinc(II) chloride; In dichloromethane; at 20 ℃; for 0.333333h;

diethylzinc; In hexane; dichloromethane; at -40 ℃; for 6h; optical yield given as %de; diastereoselective reaction;
DOI:10.1002/hlca.201000024

Reference yield:

: 1257420-17-9
(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate

: 1257420-23-7
C₁₂H₁₆O₃

Guidance literature:: (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl (2R)-2-(4-ethylphenyl)-2-hydroxybutanoate; With water; potassium hydroxide; In methanol; Reflux;

With hydrogenchloride; In water;
DOI:10.1002/hlca.201000024