1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine

Base Information

• Chemical Name: 1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine
• CAS No.: 342894-91-1
• Molecular Formula: C₁₅H₂₁N
• Molecular Weight: 215.338
• Mol file: 342894-91-1.mol

Synonyms:1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine

Chemical Property of 1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine

There total 10 articles about 1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dimethyl-2-phenethyl-pyridinium iodide (75835-06-2) → 1,4-dimethyl-2-phenethyl-1,2,3,6-tetrahydro-pyridine (1155854-72-0) + 1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine (342894-91-1)

Guidance literature:

With sodium hydroxide; sodium tetrahydroborate; In methanol; water; at 60 ℃; for 1h;

Reference yield:

phenylacetylene (536-74-3) → 1,4-dimethyl-2-phenethyl-1,2,3,6-tetrahydro-pyridine (1155854-72-0) + 1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine (342894-91-1)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 20 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / methanol / 20 h / 20 °C / 2585.81 Torr

3: acetonitrile / 20 - 35 °C

4: sodium tetrahydroborate; sodium hydroxide / methanol; water / 1 h / 60 °C

With bis-triphenylphosphine-palladium(II) chloride; sodium tetrahydroborate; copper(l) iodide; palladium 10% on activated carbon; hydrogen; triethylamine; sodium hydroxide; In methanol; water; acetonitrile;

Reference yield:

2-Bromo-4-picoline (4926-28-7) → 1,4-dimethyl-2-phenethyl-1,2,3,6-tetrahydro-pyridine (1155854-72-0) + 1,4-dimethyl-6-phenethyl-1,2,3,6-tetrahydro-pyridine (342894-91-1)

Guidance literature:

Multi-step reaction with 4 steps

1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine / 20 °C / Inert atmosphere

2: palladium 10% on activated carbon; hydrogen / methanol / 20 h / 20 °C / 2585.81 Torr

3: acetonitrile / 20 - 35 °C

4: sodium tetrahydroborate; sodium hydroxide / methanol; water / 1 h / 60 °C

With bis-triphenylphosphine-palladium(II) chloride; sodium tetrahydroborate; copper(l) iodide; palladium 10% on activated carbon; hydrogen; triethylamine; sodium hydroxide; In methanol; water; acetonitrile;

upstream raw materials:

1,4-dimethyl-2-phenethyl-pyridinium iodide

4-methyl-2-styryl-pyridine

methyl-4 (phenyl-2 ethyl)-2 pyridine

2-(4-methyl(2-pyridyl))-1-phenylethan-1-ol