N⁶-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine

Base Information

• Chemical Name: N⁶-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine
• CAS No.: 132849-50-4
• Molecular Formula: C₃₇H₃₂ClN₅O₅
• Molecular Weight: 662.145

Synonyms:N⁶-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine

Chemical Property of N⁶-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁶-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine

There total 6 articles about N⁶-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

N6-Benzoyl-9-<5'-O-<(tert-butyl)dimethylsilyl>-3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine (132849-49-1) → N6-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine (132849-50-4)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 0.5h; Ambient temperature;

DOI:10.1002/hlca.19910740104

Reference yield:

9-(3'-Chloro-3'-deoxy-β-D-xylofuranosyl)adenine (37731-77-4) → N6-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine (132849-50-4)

Guidance literature:

Multi-step reaction with 4 steps

2: 80 percent / pyridine / 3 h / Ambient temperature

3: 66 percent / pyridine / 120 h / 50 °C

4: 88 percent / Bu₄NF / tetrahydrofuran / 0.5 h / Ambient temperature

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1002/hlca.19910740104

Reference yield:

N6-Benzoyl-9-(3'-chloro-3'-deoxy-β-D-xylofuranosyl)adenine (132849-44-6) → N6-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine (132849-50-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 80 percent / pyridine / 3 h / Ambient temperature

2: 66 percent / pyridine / 120 h / 50 °C

3: 88 percent / Bu₄NF / tetrahydrofuran / 0.5 h / Ambient temperature

With pyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran;

DOI:10.1002/hlca.19910740104

upstream raw materials:

N⁶-Benzoyl-9-<5'-O-<(tert-butyl)dimethylsilyl>-3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine

9-(3'-Chloro-3'-deoxy-β-D-xylofuranosyl)adenine

N⁶-Benzoyl-9-(3'-chloro-3'-deoxy-β-D-xylofuranosyl)adenine

N⁶-Benzoyl-9-<5'-O-<(tert-butyl)dimethylsilyl>-3'-chloro-3'-deoxy-β-D-xylofuranosyl>adenine

Downstream raw materials:

N⁶-Benzoyl-3'-O-<(tert-butyl)dimethylsilyl>-5'-O-(monomethoxytrityl)adenylyl-<2'-P-(2,5-dichlorophenyl)>->5'>-N⁶-benzoyl-3'-O-<(tert-butyl)dimethylsilyl>adenylyl-<2'-P-(2,5-dichlorophenyl)>->5'>-N⁶-benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(mo...

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 132849-50-4 N⁶-Benzoyl-9-<3'-chloro-3'-deoxy-2'-O-(monomethoxytrityl)-β-D-xylofuranosyl>adenine

Send

Send

Metric Ton KG G Pound L ML

Send

Send