Technology Process of 3-phenethylisoindolin-1-one
There total 7 articles about 3-phenethylisoindolin-1-one which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium 10% on activated carbon; hydrogen;
In
methanol;
at 20 ℃;
for 4h;
under 760.051 Torr;
Schlenk technique;
Inert atmosphere;
DOI:10.1021/acs.orglett.5b01197
- Guidance literature:
-
Multi-step reaction with 5 steps
1: zinc trifluoromethanesulfonate / chloroform / 24 h / 25 °C / Inert atmosphere; Schlenk technique
2: ammonium cerium (IV) nitrate / acetonitrile; water / 0.08 h / 0 °C
3: sodium tetrahydroborate / methanol / 20 °C / Cooling with ice
4: methanesulfonyl chloride; aluminum oxide / dichloromethane / 6.5 h / 0 - 20 °C
5: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / 760.05 Torr / Schlenk technique; Inert atmosphere
With
aluminum oxide; sodium tetrahydroborate; ammonium cerium (IV) nitrate; palladium 10% on activated carbon; hydrogen; zinc trifluoromethanesulfonate; methanesulfonyl chloride;
In
methanol; dichloromethane; chloroform; water; acetonitrile;
DOI:10.1021/acs.orglett.5b01197
- Guidance literature:
-
Multi-step reaction with 5 steps
1: zinc trifluoromethanesulfonate / chloroform / 24 h / 25 °C / Inert atmosphere; Schlenk technique
2: ammonium cerium (IV) nitrate / acetonitrile; water / 0.08 h / 0 °C
3: sodium tetrahydroborate / methanol / 20 °C / Cooling with ice
4: methanesulfonyl chloride; aluminum oxide / dichloromethane / 6.5 h / 0 - 20 °C
5: hydrogen; palladium 10% on activated carbon / methanol / 4 h / 20 °C / 760.05 Torr / Schlenk technique; Inert atmosphere
With
aluminum oxide; sodium tetrahydroborate; ammonium cerium (IV) nitrate; palladium 10% on activated carbon; hydrogen; zinc trifluoromethanesulfonate; methanesulfonyl chloride;
In
methanol; dichloromethane; chloroform; water; acetonitrile;
DOI:10.1021/acs.orglett.5b01197
