ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate

Base Information

Chemical Name:ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate
CAS No.:1239332-18-3
Molecular Formula:C₂₄H₃₀N₂O₃Si
Molecular Weight:422.599
Hs Code.:

Synonyms:ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate

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Chemical Property of ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate

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Technology Process of ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate

There total 1 articles about ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1239332-17-2
ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-5-yl)benzoate

: 1239332-18-3
ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate

Guidance literature:: With (2-trimethylethylsilylethoxy)methyl chloride; In acetonitrile; at 80 ℃; for 24h;
DOI:10.1021/jo100727j

Reference yield: 74.0%

: 1239332-18-3
ethyl 3-(2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate

: 586-77-6
4-bromo-N,N-dimethylaniline

: 1239332-19-4
ethyl 3-(5-(4-(dimethylamino)phenyl)-2-phenyl-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-imidazol-4-yl)benzoate

Guidance literature:: With palladium diacetate; potassium carbonate; catacxium A; In N,N-dimethyl acetamide; at 120 ℃; for 20h; regioselective reaction; Inert atmosphere;
DOI:10.1021/jo100727j