1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one

Base Information

• Chemical Name: 1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one
• CAS No.: 641629-41-6
• Molecular Formula: C₂₃H₂₀N₄O₃
• Molecular Weight: 400.437
• Mol file: 641629-41-6.mol

Synonyms:1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one

Chemical Property of 1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one

There total 10 articles about 1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

acetic anhydride (108-24-7) + 1-N-allyl-3-[5-(hydroxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one (641629-40-5) → 1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one (641629-41-6)

Guidance literature:

With pyridine; at 20 ℃;

DOI:10.1016/S0008-6215(03)00376-8

Reference yield: 68.0%

3-<5-(Acetoxymethyl)-1-phenylpyrazol-3-yl>quinoxalin-2(1H)-one (66895-41-8) + allyl bromide (106-95-6) → 1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one (641629-41-6)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1016/S0008-6215(03)00376-8

Reference yield: 57.0%

1-N-allyl-3-[3,4-di-O-acetyl-2-deoxy-1-(phenylhydrazono)but-2-en-1-yl]quinoxalin-2-one → 1-N-allyl-3-[5-(acetoxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one (641629-41-6)

Guidance literature:

With acetic anhydride; Heating;

DOI:10.1016/S0008-6215(03)00376-8

upstream raw materials:

3-<5-(Acetoxymethyl)-1-phenylpyrazol-3-yl>quinoxalin-2(1H)-one

allyl bromide

acetic anhydride

1-N-allyl-3-[5-(hydroxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one

Downstream raw materials:

1-N-(2,3-dibromopropyl)-3-[5-(hydroxymethyl)-1-(4-bromophenyl)pyrazol-3-yl]quinoxalin-2-one

1-N-(2,3-dihydroxypropyl)-3-[5-(hydroxymethyl)-1-phenylpyrazol-3-yl]quinoxalin-2-one