methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate

Base Information

• Chemical Name: methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate
• CAS No.: 104226-72-4
• Molecular Formula: C₂₁H₂₄O₅
• Molecular Weight: 356.419
• Mol file: 104226-72-4.mol

Synonyms:methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate

Chemical Property of methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate

There total 2 articles about methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(4-methoxyphenyl)propionyl chloride (15893-42-2) + (1E,3E,5E)-1,6-bis(trimethylsilyl)hexa-1,3,5-triene (133683-82-6) + 3-Chlorocarbonyl-propionic acid methyl ester; compound with GENERIC INORGANIC NEUTRAL COMPONENT → methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate (104226-72-4)

Guidance literature:

With aluminium trichloride; Yield given. Multistep reaction; 1.) CH₂Cl₂, 0 deg C, 1 h, 2.) CH₂Cl₂, from 0 deg C to RT, 1 h;

DOI:10.1080/00397919308009765

Reference yield:

→ methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate (104226-72-4)

Guidance literature:

Reference yield: 36.0%

methyl (5E,7E,9E)-4,11-dioxo-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate (104226-72-4) → 5-[(1E,3E,5E)-7-Hydroxy-9-(4-methoxy-phenyl)-nona-1,3,5-trienyl]-dihydro-furan-2-one + methyl (5E,7E,9E)-4,11-dihydroxy-13-(p-methoxyphenyl)-trideca-5,7,9-trienoate

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 ℃; for 0.5h;

DOI:10.1080/00397919308009765

upstream raw materials:

3-(4-methoxyphenyl)propionyl chloride

(1E,3E,5E)-1,6-bis(trimethylsilyl)hexa-1,3,5-triene

Downstream raw materials:

(5E,7E,9E)-N,N-tetramethylene-4,11-dihydroxy-13-(p-methoxyphenyl)-trideca-5,7,9-trienamide

(5E,7Z,9E)-N,N-tetramethylene-4,11-dihydroxy-13-(p-methoxyphenyl)-trideca-5,7,9-trienamide