3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone

Base Information

• Chemical Name: 3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone
• CAS No.: 85738-90-5
• Molecular Formula: C₂₁H₂₃ClO₄
• Molecular Weight: 374.864
• Mol file: 85738-90-5.mol

Synonyms:3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone

Chemical Property of 3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone

There total 1 articles about 3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

2,3-Dichloro-1,4-naphthoquinone (117-80-6) + tert-butyl cyclohexanecarboxylate (16537-05-6) → 3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone (85738-90-5)

Guidance literature:

With lithium dicyclohexylamide; In tetrahydrofuran; hexane; 1.) -70 deg C, 1 h, 2.) -35 deg C, 1 h, room temperature;

DOI:10.1039/P19830000035

Reference yield: 94.0%

3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone (85738-90-5) → 2-(1-carboxycyclohexyl)-3-chloro-1,4-naphthoquinone (85738-93-8)

Guidance literature:

With hydrogenchloride; In 1,2-dimethoxyethane; for 1h; Heating; further solvent;

DOI:10.1039/P19830000035

Reference yield: 91.5%

3-chloro-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone (85738-90-5) → 3-hydroxy-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone (85738-92-7)

Guidance literature:

With potassium hydroxide; In methanol; water; for 0.333333h; Heating;

DOI:10.1039/P19830000035

upstream raw materials:

2,3-Dichloro-1,4-naphthoquinone

tert-butyl cyclohexanecarboxylate

Downstream raw materials:

2-(1-carboxycyclohexyl)-3-chloro-1,4-naphthoquinone

3-hydroxy-2-(1-t-butoxycarbonylcyclohexyl)-1,4-naphthoquinone

2-(1-carboxycyclohexyl)-3-hydroxy-1,4-naphthoquinone