2-Methyl-3-phenylpiperazine

Base Information

Chemical Name:2-Methyl-3-phenylpiperazine
CAS No.:104096-26-6
Molecular Formula:C11H16 N2
Molecular Weight:176.261
Hs Code.:2933599090
DSSTox Substance ID:DTXSID30331319
Nikkaji Number:J3.202.650H
Mol file:104096-26-6.mol

Synonyms:2-methyl-3-phenylpiperazine;104096-26-6;Piperazine, 2-methyl-3-phenyl- (6CI,9CI);2-Methyl-3-phenyl-piperazin;SCHEMBL10349649;DTXSID30331319

Suppliers and Price of 2-Methyl-3-phenylpiperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-Methyl-3-phenylpiperazine

Chemical Property:

PSA：24.06000
LogP:1.96660
XLogP3:1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:176.131348519
Heavy Atom Count:13
Complexity:152

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(NCCN1)C2=CC=CC=C2

Technology Process of 2-Methyl-3-phenylpiperazine

There total 6 articles about 2-Methyl-3-phenylpiperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1421005-01-7
C₂₅H₂₈N₂

: 104096-26-6
2-Methyl-3-phenylpiperazine

Guidance literature:: With palladium on activated charcoal; hydrogen; In methanol; for 4h;
DOI:10.1016/j.tetlet.2012.11.110

Reference yield: 44.0%

: 107-15-3,85404-18-8
ethylenediamine

: 22596-45-8
2-methyl-2-nitro-3-phenyloxirane

: 104096-26-6
2-Methyl-3-phenylpiperazine

Guidance literature:: ethylenediamine; 2-methyl-2-nitro-3-phenyloxirane; In ethanol; at 20 ℃; for 6h; Inert atmosphere;

With sodium tris(acetoxy)borohydride; In ethanol; water; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1021/ol500444z

Reference yield:

: 107-15-3,85404-18-8
ethylenediamine

: 579-07-7
1-Phenylpropane-1,2-dione

: 104096-26-6
2-Methyl-3-phenylpiperazine

Guidance literature:: With glucose-6-phosphate dehydrogenase; glucose-6-phosphate; Myxococcus stipitatus R-selective imine reductase; NADPH; magnesium chloride; In aq. phosphate buffer; at 25 ℃; for 4h; pH=7; Enzymatic reaction;
DOI:10.1021/acscatal.8b00291