N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester

Base Information

• Chemical Name: N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester
• CAS No.: 1365570-76-8
• Molecular Formula: C₂₆H₃₀BrNO₅
• Molecular Weight: 516.432

Synonyms:N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester

Chemical Property of N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester

There total 3 articles about N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

C23H28BrNO5 (1365570-63-3) + propargyl bromide (106-96-7) → N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester (1365570-76-8)

Guidance literature:

C₂₃H₂₈BrNO₅; With potassium carbonate; In acetonitrile; for 0.5h; Inert atmosphere;

propargyl bromide; In acetonitrile; at 40 ℃; for 8h; Inert atmosphere;

DOI:10.1007/s11164-011-0429-1

Reference yield:

L-phenylalanine (63-91-2,25191-15-5,658-69-5,67675-33-6) → N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester (1365570-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol; dichloromethane / 24 h / 40 °C / Inert atmosphere

2.1: potassium carbonate / acetonitrile / 0.5 h / Inert atmosphere

2.2: 8 h / 40 °C / Inert atmosphere

With potassium carbonate; potassium hydroxide; In ethanol; dichloromethane; acetonitrile;

DOI:10.1016/j.tet.2012.01.092

Reference yield:

C14H18Br2O3 (198008-33-2) → N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester (1365570-76-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol; dichloromethane / 24 h / 40 °C / Inert atmosphere

2.1: potassium carbonate / acetonitrile / 0.5 h / Inert atmosphere

2.2: 8 h / 40 °C / Inert atmosphere

With potassium carbonate; potassium hydroxide; In ethanol; dichloromethane; acetonitrile;

DOI:10.1016/j.tet.2012.01.092

upstream raw materials:

C₂₃H₂₈BrNO₅

propargyl bromide

C₁₄H₁₈Br₂O₃

L-phenylalanine

Downstream raw materials:

(S)-(1-hexyl-1H-1,2,3-triazol-4-yl)methyl 2-((S)-4-bromo-5-oxo-2-((1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl-oxy)-2,5-dihydrofuran-3-ylamino)-3-phenylpropanoate

(S)-(1-benzyl-1H-1,2,3-triazol-4-yl)methyl 2-((S)-4-bromo-5-oxo-2-((1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yloxy)-2,5-dihydrofuran-3-ylamino)-3-phenylpropanoate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1365570-76-8 N-[3-bromo-5-(S)-bornyloxy-2(5H)-furanonyl] (S)-phenylalanine propargyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send