O-acetyl-7,8-seco-<2(R)-piperidinecarboxylic acid>⁸-cyclosporin-7-thiocarboxylic acid S-benzyl ester

Base Information

• Chemical Name: O-acetyl-7,8-seco-<2(R)-piperidinecarboxylic acid>⁸-cyclosporin-7-thiocarboxylic acid S-benzyl ester
• CAS No.: 164029-01-0
• Molecular Formula: C₇₄H₁₂₅N₁₁O₁₃S
• Molecular Weight: 1408.94

Synonyms:O-acetyl-7,8-seco-<2(R)-piperidinecarboxylic acid>⁸-cyclosporin-7-thiocarboxylic acid S-benzyl ester

Chemical Property of O-acetyl-7,8-seco-<2(R)-piperidinecarboxylic acid>⁸-cyclosporin-7-thiocarboxylic acid S-benzyl ester

Chemical Property:

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Technology Process of O-acetyl-7,8-seco-<2(R)-piperidinecarboxylic acid>⁸-cyclosporin-7-thiocarboxylic acid S-benzyl ester

There total 1 articles about O-acetyl-7,8-seco-<2(R)-piperidinecarboxylic acid>⁸-cyclosporin-7-thiocarboxylic acid S-benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

O-acetyl-N-Boc-7,8-seco-<2(R)-piperidinecarboxylic acid>8-cyclosporin-7-thiocarboxylic acid S-benzyl ester → O-acetyl-7,8-seco-<2(R)-piperidinecarboxylic acid>8-cyclosporin-7-thiocarboxylic acid S-benzyl ester (164029-01-0)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; for 3h; Ambient temperature;

DOI:10.1021/jm00011a004

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