6,9-Dimethoxyphenazine-1-carboxylic acid

Base Information

• Chemical Name: 6,9-Dimethoxyphenazine-1-carboxylic acid
• CAS No.: 103942-91-2
• Molecular Formula: C₁₅H₁₂N₂O₄
• Molecular Weight: 284.271
• Hs Code.: 2933990090
• ChEMBL ID: CHEMBL4171018
• DSSTox Substance ID: DTXSID20587520
• Wikidata: Q82479973
• Mol file: 103942-91-2.mol

Synonyms:6,9-dimethoxyphenazine-1-carboxylic acid;103942-91-2;6,9-Dimethoxy-phenazine-1-carboxylic acid;MFCD00705271;CHEMBL4171018;SCHEMBL10866827;DTXSID20587520;AKOS005256856;MCULE-6023718889;6,9-Dimethoxyphenazine-1-carboxylicacid;BENZIMIDAZOLE-2-CARBOXYLICACIDMETHYLESTER

Chemical Property of 6,9-Dimethoxyphenazine-1-carboxylic acid

Chemical Property:

• Vapor Pressure: 3.61E-13mmHg at 25°C
• Refractive Index: 1.692
• Boiling Point: 555.4°Cat760mmHg
• Flash Point: 289.7°C
• PSA: 81.54000
• Density: 1.389g/cm³
• LogP: 2.49840
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 284.07970687
• Heavy Atom Count: 21
• Complexity: 392

Purity/Quality:

97% ^*data from raw suppliers

6,9-DIMETHOXY-PHENAZINE-1-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C2=NC3=C(C=CC=C3N=C12)C(=O)O)OC

Technology Process of 6,9-Dimethoxyphenazine-1-carboxylic acid

There total 3 articles about 6,9-Dimethoxyphenazine-1-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

C15H14N2O6 → 6,9-dimethoxyphenazine-1-carboxylic acid (103942-91-2)

Guidance literature:

With sodium tetrahydroborate; sodium hydroxide; In water; at 80 ℃; for 16h;

DOI:10.1016/j.ejmech.2017.11.026

Reference yield:

3-nitroanthranilic acid (606-18-8) + 2,5-dimethoxyaniline (102-56-7,102526-87-4) → 6,9-dimethoxyphenazine-1-carboxylic acid (103942-91-2)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(I) bromide; copper / ethanol / Reflux

2: sodium hydroxide; sodium tetrahydroborate / water / 16 h / 80 °C

With sodium tetrahydroborate; copper; copper(I) bromide; sodium hydroxide; In ethanol; water;

DOI:10.1016/j.ejmech.2017.11.026

Reference yield:

1,4-dimethoxy-2-nitrobenzene (89-39-4) + anthranilic acid (118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4) → 6,9-dimethoxyphenazine-1-carboxylic acid (103942-91-2)

Guidance literature:

With potassium hydroxide; toluene;

upstream raw materials:

1,4-dimethoxy-2-nitrobenzene

anthranilic acid

3-nitroanthranilic acid

2,5-dimethoxyaniline