N-CYCLOPENTYLHYDRAZINECARBOTHIOAMIDE

Base Information

• Chemical Name: N-CYCLOPENTYLHYDRAZINECARBOTHIOAMIDE
• CAS No.: 122813-74-5
• Molecular Formula: C₆H₁₃N₃S
• Molecular Weight: 159.255
• Mol file: 122813-74-5.mol

Synonyms:4-cyclopentyl thiosemicarbazide

Chemical Property of N-CYCLOPENTYLHYDRAZINECARBOTHIOAMIDE

Chemical Property:

Purity/Quality:

3-Amino-1-cyclopentylthiourea ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-CYCLOPENTYLHYDRAZINECARBOTHIOAMIDE

There total 5 articles about N-CYCLOPENTYLHYDRAZINECARBOTHIOAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclopentyl isothiocyanate (33522-03-1) → 4-cyclopentyl thiosemicarbazide (122813-74-5)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 1.5h;

Reference yield:

cyclopentylthiocarbamoylsulfanyl-acetic acid (828299-46-3) → 4-cyclopentyl thiosemicarbazide (122813-74-5)

Guidance literature:

With hydrazine hydrate; alkaline solution;

DOI:10.1016/S0960-894X(02)00703-5

Reference yield:

Cyclopentamine (1003-03-8) → 4-cyclopentyl thiosemicarbazide (122813-74-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium hydroxide / H₂O; ethanol / 20 °C

2: sodium hydroxide; hydrazine hydrate / H₂O / 2 h / Heating

With potassium hydroxide; sodium hydroxide; hydrazine hydrate; In ethanol; water;

DOI:10.1016/j.ejps.2005.02.014

upstream raw materials:

cyclopentylthiocarbamoylsulfanyl-acetic acid

Cyclopentamine

cyclopentyl isothiocyanate

Downstream raw materials:

N-cyclopentyl-5-(4-methoxy-3,5-dimethylphenyl)-1,3,4-thiadiazol-2-amine

N-(4-acetyl-5-(2-chloro-8-methylquinolin-3-yl)-4,5-dihydro-1,3,4-thiadiazol-2-yl)-N-cyclopentylacetamide

1-((2-chloro-8-methylquinolin-3-yl)methylene)-4-cyclopentylthiosemicarbazide

{5-[3-(3-cyclopentyloxy-4-methoxyphenyl)-5-methyl-4,5-dihydro-isoxazol-5-yl]-[1,3,4]thiadiazol-2-yl}-cyclopropylamine

Refernces

• 1、 Bhat, Abdul R.,Tazeem,Azam, Amir,Choi, Inho,Athar, Fareeda. "3-(1,3,4-Thiadiazole-2-yl)quinoline derivatives: Synthesis, characterization and anti-microbial activity". scheme or table. p. 3158 - 3166. Retrieved 2011/06/26.
• 2、 -. "New 2-aminothiadiazole derivatives". Page/Page column 25. . Retrieved 2011/08/03.