N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

Base Information

Chemical Name:N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide
CAS No.:122183-13-5
Molecular Formula:C₃₂H₂₉N₅O₅
Molecular Weight:563.613
Hs Code.:

Synonyms:N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

Suppliers and Price of N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

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Technology Process of N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

There total 1 articles about N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 7536-35-8
2-nitro-3-benzyloxy-4-methylbenzoyl chloride

: 111861-12-2
2-(4-hydroxyphenyl)-5⁽⁶⁾-(1-piperazinyl)benzimidazole

: 122183-13-5
N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

Guidance literature:: With triethylamine; In chloroform; N,N-dimethyl-formamide; for 1h;

Reference yield:

: 122183-13-5
N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

: (2-Amino-3-hydroxy-4-methyl-phenyl)-{4-[2-(4-hydroxy-phenyl)-1H-benzoimidazol-5-yl]-piperazin-1-yl}-methanone

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; under 760 Torr; Ambient temperature;

Reference yield:

: 122183-13-5
N-<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinyl>-2-nitro-3-benzyloxy-4-methylbenzamide

: 122183-11-3
2-amino-4,6-dimethyl-1,9-di<4-<2-(4-hydroxyphenyl)-5(6)-benzimidazolyl>-1-piperazinylcarbonyl>-3H-3-oxophenoxyazine

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd/C / methanol / 760 Torr / Ambient temperature

2: p-quinone / methanol / 96 h / Ambient temperature

With hydrogen; p-benzoquinone; palladium on activated charcoal; In methanol;