2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE

Base Information

Chemical Name:2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE
CAS No.:103577-47-5
Molecular Formula:C₁₇H₁₆F₃N₃O₂S
Molecular Weight:383.394
Hs Code.:
Mol file:103577-47-5.mol

Synonyms:2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE

Suppliers and Price of 2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLSULFINYL]BENZIMIDAZOLE 95.00%
5MG
$ 497.87

Total 4 raw suppliers

Chemical Property of 2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE

Chemical Property:

Melting Point:178-179 °C (decomp)
Boiling Point:560.6±60.0 °C(Predicted)
PKA:9.57±0.10(Predicted)
PSA：87.08000
Density:1.46±0.1 g/cm3(Predicted)
LogP:4.68930

Purity/Quality:

99% ^*data from raw suppliers

2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)METHYLSULFINYL]BENZIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE

There total 5 articles about 2-[(4-TRIFLUOROETHOXY-3,5-DIMETHYL-2-PYRIDINYL)-METHYLSULFINYL]-BENZIMIDAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 103602-42-2
2-[3,5-Dimethyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethylsulfanyl]-1H-benzoimidazole

: 103577-47-5
2-[3,5-Dimethyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethanesulfinyl]-1H-benzoimidazole

Guidance literature:: With 3-chloro-benzenecarboperoxoic acid; In chloroform; ice-cooling;
DOI:10.1248/cpb.38.2853

Reference yield:

: 14248-66-9
3,5-dimethyl-4-nitropyridine-1-oxide

: 103577-47-5
2-[3,5-Dimethyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethanesulfinyl]-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 5 steps

1: 90 percent / tert-BuOK / 50 - 60 °C

2: 0.5 h / 110 - 120 °C

3: ammonium persulfate / methanol; H₂O / Heating

4: 1) SOCl₂, 2) MeONa / 1) CHCl₃, reflux, 2) MeOH, reflux

5: 76 percent / m-chloroperbenzoic acid / CHCl₃ / ice-cooling

With ammonium persulfate; thionyl chloride; potassium tert-butylate; sodium methylate; 3-chloro-benzenecarboperoxoic acid; In methanol; chloroform; water;
DOI:10.1248/cpb.38.2853

Reference yield:

: 103577-78-2
3,5-Dimethyl-4-(2,2,2-trifluoroethoxy)pyridine N-oxide

: 103577-47-5
2-[3,5-Dimethyl-4-(2,2,2-trifluoro-ethoxy)-pyridin-2-ylmethanesulfinyl]-1H-benzoimidazole

Guidance literature:: Multi-step reaction with 4 steps

1: 0.5 h / 110 - 120 °C

2: ammonium persulfate / methanol; H₂O / Heating

3: 1) SOCl₂, 2) MeONa / 1) CHCl₃, reflux, 2) MeOH, reflux

4: 76 percent / m-chloroperbenzoic acid / CHCl₃ / ice-cooling

With ammonium persulfate; thionyl chloride; sodium methylate; 3-chloro-benzenecarboperoxoic acid; In methanol; chloroform; water;
DOI:10.1248/cpb.38.2853