(2-BENZYLOXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

Base Information

• Chemical Name: (2-BENZYLOXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE
• CAS No.: 103535-06-4
• Molecular Formula: Br*C₂₇H₂₆OP
• Molecular Weight: 477.381
• Mol file: 103535-06-4.mol

Synonyms:[2-(Benzyloxy)ethyl]triphenylphosphoniumbromide (7CI)

Chemical Property of (2-BENZYLOXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

Chemical Property:

• PSA: 19.04000
• LogP: 5.95760

Purity/Quality:

99.90% ^*data from raw suppliers

(2-(Benzyloxy)ethyl)triphenylphosphoniumbromide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2-BENZYLOXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

There total 1 articles about (2-BENZYLOXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

bromoethyl-2-benzyl ether (1462-37-9) + triphenylphosphine (603-35-0) → (2-(benzyloxy)ethyl)triphenylphosphonium bromide (103535-06-4)

Guidance literature:

In acetonitrile; at 80 ℃; for 24h;

Reference yield: 85.0%

(2-(benzyloxy)ethyl)triphenylphosphonium bromide (103535-06-4) + (3aR)-2,2-dimethyl-(3ar,6ac)-3a,6a-dihydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde (14260-64-1) → C17H20O4

Guidance literature:

(2-(benzyloxy)ethyl)triphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; for 0.5h; Cooling with ethanol-dry ice;

(3aR)-2,2-dimethyl-(3ar,6ac)-3a,6a-dihydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde; In tetrahydrofuran; at 20 ℃; for 1.16667h;

Reference yield: 80.2%

(2S,3S)-4-(tert-butyldimethylsilyloxy)-3-methyl-1-oxobutan-2-yl acetate + (2-(benzyloxy)ethyl)triphenylphosphonium bromide (103535-06-4) → (2S,3R,E)-6-(benzyloxy)-1-(tert-butyldimethylsilyloxy)-2-methylhex-4-en-3-yl acetate

Guidance literature:

(2-(benzyloxy)ethyl)triphenylphosphonium bromide; With potassium hexamethylsilazane; In tetrahydrofuran; toluene; at -65 ℃; for 0.25h;

(2S,3S)-4-(tert-butyldimethylsilyloxy)-3-methyl-1-oxobutan-2-yl acetate; In tetrahydrofuran; toluene; at -65 - -10 ℃; for 1.5h;

DOI:10.1002/ejoc.201800875

upstream raw materials:

bromoethyl-2-benzyl ether

triphenylphosphine

Downstream raw materials:

benzyl cinnamyl ether