3t-phenyl-acrylonitrile N-oxide

Base Information

• Chemical Name: 3t-phenyl-acrylonitrile N-oxide
• CAS No.: 93970-65-1
• Molecular Formula: C₉H₇NO
• Molecular Weight: 145.161
• Mol file: 93970-65-1.mol

Synonyms:3t-phenyl-acrylonitrile N-oxide

Chemical Property of 3t-phenyl-acrylonitrile N-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3t-phenyl-acrylonitrile N-oxide

There total 4 articles about 3t-phenyl-acrylonitrile N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

cinnamaldehyde oxime (59336-59-3) → 3t-phenyl-acrylonitrile N-oxide (93970-65-1)

Guidance literature:

With pyridine; N-chloro-succinimide; at 60 ℃; for 0.5h;

DOI:10.1016/S0960-894X(02)00179-8

Reference yield:

(2E)-N-hydroxy-3-phenylacrylimidoyl chloride (105363-16-4) → 3t-phenyl-acrylonitrile N-oxide (93970-65-1)

Guidance literature:

With triethylamine; In 1,2-dichloro-ethane; at 0 ℃; for 0.05h; Cooling with ice; Inert atmosphere;

DOI:10.1002/chem.200903484

Reference yield:

(E)-3-phenylpropenal (14371-10-9) → 3t-phenyl-acrylonitrile N-oxide (93970-65-1)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium hydroxide / 2-methyl-propan-2-ol; H₂O / 0.5 h / 20 °C

2: chloramine-T trihydrate / 2-methyl-propan-2-ol; H₂O / 0.08 h / 20 °C

With sodium hydroxide; hydroxylamine hydrochloride; chloroamine-T; In water; tert-butyl alcohol;

DOI:10.1021/jo050163b

upstream raw materials:

cinnamaldehyde oxime

(E)-3-phenylpropenal

3-phenyl-propenal

(2E)-N-hydroxy-3-phenylacrylimidoyl chloride

Downstream raw materials:

5-(4-chloro-phenyl)-3-trans-styryl-4,5-dihydro-isoxazole

3-trans-styryl-4,5-dihydro-isoxazole-5-carboxylic acid amide

(3-trans-styryl-[1,2,4]oxadiazol-5-yl)-guanidine

4-(5-phenyl-3-trans-styryl-4,5-dihydro-isoxazol-5-yl)-morpholine