FMOC-LYS(Z)-CL

Base Information

Chemical Name:FMOC-LYS(Z)-CL
CAS No.:103321-56-8
Molecular Formula:C29H29 Cl N2 O5
Molecular Weight:521.013
Hs Code.:
Mol file:103321-56-8.mol

Synonyms:Carbamicacid, [5-(chlorocarbonyl)-5-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]pentyl]-,phenylmethyl ester, (S)-

Suppliers and Price of FMOC-LYS(Z)-CL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
Fmoc-Ne-Z-L-lysylChloride 97
250g
$ 2658.00

Labseeker
Fmoc-Ne-Z-L-lysylChloride 97
50g
$ 1283.00

American Custom Chemicals Corporation
FMOC-LYS(Z)-CL 95.00%
5MG
$ 498.76

Total 9 raw suppliers

Chemical Property of FMOC-LYS(Z)-CL

Chemical Property:

Boiling Point:715.9±60.0 °C(Predicted)
PKA:10.31±0.46(Predicted)
PSA：93.73000
Density:1.264±0.06 g/cm3(Predicted)
LogP:6.53760
Storage Temp.:Store at 0°C

Purity/Quality:

98%Min ^*data from raw suppliers

Fmoc-Ne-Z-L-lysylChloride 97 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of FMOC-LYS(Z)-CL

There total 1 articles about FMOC-LYS(Z)-CL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 86060-82-4,110990-07-3
Fmoc-Lys(Z)-OH

: 103321-56-8
FMOC-Lys(Z)-Cl

Guidance literature:: With thionyl chloride; In dichloromethane; for 0.5h; Yield given; Heating;
DOI:10.1021/jo00289a056

Reference yield:

: 103321-56-8
FMOC-Lys(Z)-Cl

: 81167-39-7
methyl N-(diphenylmethylene)glycinate

: 2-(benzhydrylidene-amino)-8-benzyloxycarbonylamino-4-(9H-fluoren-9-ylmethoxycarbonylamino)-3-oxo-octanoic acid methyl ester

Guidance literature:: methyl N-(diphenylmethylene)glycinate; With potassium tert-butylate; In tetrahydrofuran; at -78 ℃; for 0.5h;

FMOC-Lys(Z)-Cl; In tetrahydrofuran; at -78 ℃; for 0.5h;
DOI:10.1021/ol035673b

Reference yield:

: 103321-56-8
FMOC-Lys(Z)-Cl

: 123622-45-7
H-Lys(Z)-Pro-Lys(Z)-Pro-NHC₁₂H₂₅₄*HCl

Guidance literature:: Multi-step reaction with 6 steps

1: 5percent Na₂CO₃ / CHCl₃ / 0.17 h

2: 4-(aminomethyl)-piperidine (4-AMP) / CHCl₃ / 0.5 h

3: 5percent Na₂CO₃ / CHCl₃ / 0.17 h

4: 4-(aminomethyl)-piperidine (4-AMP) / CHCl₃ / 0.5 h

5: 5percent Na₂CO₃ / CHCl₃ / 0.17 h

6: 1) 4-(aminomethyl)-piperidine (4-AMP), 2) 4 N HCl / 1) CHCl₃, 30 min, 2) ethyl acetate

With hydrogenchloride; sodium carbonate; 4-Aminomethylpiperidine; In chloroform;
DOI:10.1021/jo00289a056