4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID METHYL ESTER ACETATE

Base Information

• Chemical Name: 4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID METHYL ESTER ACETATE
• CAS No.: 103260-78-2
• Molecular Formula: C10H16 O4
• Molecular Weight: 200.235
• Hs Code.: 2918990090
• Mol file: 103260-78-2.mol

Synonyms:Cyclohexanecarboxylicacid, 4-hydroxy-, methyl ester, acetate (6CI)

Chemical Property of 4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID METHYL ESTER ACETATE

Chemical Property:

• Vapor Pressure: 0.0226mmHg at 25°C
• Refractive Index: 1.457
• Boiling Point: 249.7°Cat760mmHg
• Flash Point: 115.4°C
• PSA: 52.60000
• Density: 1.09g/cm³
• LogP: 1.28130

Purity/Quality:

98%min ^*data from raw suppliers

4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID METHYL ESTER ACETATE 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID METHYL ESTER ACETATE

There total 9 articles about 4-HYDROXY-CYCLOHEXANECARBOXYLIC ACID METHYL ESTER ACETATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxycyclohexanecarboxylic acid (3685-22-1,3685-26-5,17419-81-7) → cis-4-acetoxy-cyclohexanecarboxylic acid methyl ester (103260-78-2)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

With pyridine;

DOI:10.1039/jr9500001379

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + cis-4-hydroxycyclohexanecarboxylic acid (3685-26-5,17419-81-7,3685-22-1) + acetic anhydride (108-24-7) → cis-4-acetoxy-cyclohexanecarboxylic acid methyl ester (103260-78-2)

Guidance literature:

With pyridine; diethyl ether;

DOI:10.1021/ja01569a030

Reference yield:

sulfuric acid (7664-93-9) + cis-3-Methoxycyclohexanecarboxylic acid (73873-52-6) + acetic anhydride (108-24-7) → methyl cyclohex-3-ene-1-carboxylate (6493-77-2) + trans-4-acetoxy-cyclohexanecarboxylic acid methyl ester (103260-78-2)

Guidance literature:

DOI:10.1021/ja01569a030

upstream raw materials:

diazomethane

trans-4-acetoxy-cyclohexanecarboxylic acid

sulfuric acid

cis-3-Methoxycyclohexanecarboxylic acid