C₁₇H₂₈F₃NO₂Si

Base Information

• Chemical Name: C₁₇H₂₈F₃NO₂Si
• CAS No.: 1227306-87-7
• Molecular Formula: C₁₇H₂₈F₃NO₂Si
• Molecular Weight: 363.496
• Mol file: 1227306-87-7.mol

Synonyms:C₁₇H₂₈F₃NO₂Si

Chemical Property of C₁₇H₂₈F₃NO₂Si

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₁₇H₂₈F₃NO₂Si

There total 1 articles about C₁₇H₂₈F₃NO₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

C14H22F3NOSi (1227306-95-7) + methyloxirane (75-56-9,16033-71-9) → C17H28F3NO2Si (1227306-87-7)

Guidance literature:

With zirconium(IV) chloride; at 20 ℃; Inert atmosphere;

DOI:10.1021/ml300209g

Reference yield: 52.0%

3,3-Dimethylacryloyl chloride (3350-78-5) + C17H28F3NO2Si (1227306-87-7) → C22H34F3NO3Si (1227306-88-8)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; chemoselective reaction; Inert atmosphere;

DOI:10.1021/ml300209g

Reference yield:

C17H28F3NO2Si (1227306-87-7) → C31H27F3N2O3P

Guidance literature:

Multi-step reaction with 6 steps

1.1: triethylamine / dichloromethane / 0 °C / Inert atmosphere

2.1: 2-chloropropionyl chloride / methanol / 20 °C / Inert atmosphere

3.1: 1,1'-azodicarbonyl-dipiperidine; tributylphosphine / tetrahydrofuran / 20 - 80 °C / Inert atmosphere

4.1: hydrazine hydrate / methanol; dichloromethane / 2 h / 20 °C / Inert atmosphere; Acidic conditions

4.2: 80 °C

5.1: ozone; oxygen / methanol; dichloromethane / 1 h / -78 °C / Inert atmosphere

6.1: 1,2-dichloro-ethane; acetonitrile / 5 h / Inert atmosphere; Heating

With hydrazine hydrate; 2-chloropropionyl chloride; tributylphosphine; oxygen; ozone; triethylamine; 1,1'-azodicarbonyl-dipiperidine; In tetrahydrofuran; methanol; dichloromethane; 1,2-dichloro-ethane; acetonitrile; 3.1: |Mitsunobu Displacement;

DOI:10.1021/ml300209g

upstream raw materials:

C₁₄H₂₂F₃NOSi

methyloxirane

Downstream raw materials:

C₂₂H₃₄F₃NO₃Si

C₂₄H₂₃F₃N₂O₅

C₁₃H₁₃F₃N₂O₃

C₁₆H₂₀F₃NO₃