4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene

Base Information

• Chemical Name: 4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene
• CAS No.: 1025383-14-5
• Molecular Formula: C₂₉H₄₆O₆SSi
• Molecular Weight: 550.832
• Mol file: 1025383-14-5.mol

Synonyms:4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene

Chemical Property of 4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene

There total 1 articles about 4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

4-methanesulfonyloxy-3-methoxyphenol (1025383-10-1) + C23H40O4Si (1025382-74-4) → 4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene (1025383-14-5)

Guidance literature:

4-methanesulfonyloxy-3-methoxyphenol; With 1,8-diazabicyclo[5.4.0]undec-7-ene; copper dichloride; In acetonitrile; at -20 ℃; for 0.25h; Inert atmosphere;

C₂₃H₄₀O₄Si; In acetonitrile; at 0 - 20 ℃; for 17h; Inert atmosphere;

DOI:10.1039/b901358j

Reference yield: 76.0%

4-methanesulfonyloxy-3-methoxy-((6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy)benzene (1025383-14-5) → 4-[(6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy]-2-methoxyphenol (1025383-06-5)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 2h; Inert atmosphere;

DOI:10.1039/b901358j

upstream raw materials:

4-methanesulfonyloxy-3-methoxyphenol

C₂₃H₄₀O₄Si

Downstream raw materials:

4-[(6'E,10'E)-12'-tert-butyldimethylsiloxy-3',7',11'-trimethyldodeca-6',10'-dien-1'-yn-3'-yloxy]-2-methoxyphenol