2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

Base Information

Chemical Name:2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone
CAS No.:321569-98-6
Molecular Formula:C₄₈H₄₀O₇
Molecular Weight:728.841
Hs Code.:

Synonyms:2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

Suppliers and Price of 2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

There total 10 articles about 2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 115-19-5
2-methyl-but-3-yn-2-ol

: 321569-95-3
2',4',5,7-tetrakis(benzyloxy)-6-iodoisoflavone

: 321569-98-6
2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

Guidance literature:: With copper(l) iodide; triethylamine; triphenylphosphine; palladium dichloride; In N,N-dimethyl-formamide; at 75 ℃; for 2h;
DOI:10.1246/cl.2000.1362

Reference yield:

: 321569-92-0
1-[6-benzoyloxy-2,4-bis(benzyloxy)-3-iodophenyl]-2-[2,4-bis(benzyloxy)phenyl]-3,3-dimethoxypropan-1-one

: 321569-98-6
2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

Guidance literature:: Multi-step reaction with 2 steps

1: 995 mg / aq. NaOH / dioxane; methanol / 2 h / 20 °C

2: 71 percent / Et₃N; PdCl₂; PPh₃ / CuI / dimethylformamide / 2 h / 75 °C

With sodium hydroxide; triethylamine; triphenylphosphine; palladium dichloride; copper(l) iodide; In 1,4-dioxane; methanol; N,N-dimethyl-formamide;
DOI:10.1248/cpb.52.1285

Reference yield:

: 71386-98-6
2',4'-dihydroxy-6'-(methoxymethoxy)acetophenone

: 321569-98-6
2',4',5,7-tetrakis(benzyloxy)-6-(3-hydroxy-3-methyl-1-butynyl)isoflavone

Guidance literature:: Multi-step reaction with 8 steps

1: 92 percent / I₂; aq. HIO₄ / ethanol / 0.5 h / 40 °C

2: 80 percent / K₂CO₃ / dimethylformamide / 0.5 h / 70 °C

3: KOH / ethanol / 0.75 h / 80 °C

4: 2.35 g / aq. HCl / CHCl₃; methanol / 1 h / 40 °C

5: 530 mg / pyridine / 0.5 h / 70 °C

6: thallium(III) nitrate trihydrate / CHCl₃ / 4 h / 30 °C

7: 218 mg / aq. NaOH / dioxane; methanol / 2 h / 20 °C

8: 71 percent / Et₃N; PdCl₂; PPh₃ / CuI / dimethylformamide / 2 h / 75 °C

With pyridine; hydrogenchloride; potassium hydroxide; sodium hydroxide; thallium(III) nitrate trihydrate; iodine; potassium carbonate; periodic acid; triethylamine; triphenylphosphine; palladium dichloride; copper(l) iodide; In 1,4-dioxane; methanol; ethanol; chloroform; N,N-dimethyl-formamide;
DOI:10.1248/cpb.52.1285