2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Base Information

• Chemical Name: 2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
• CAS No.: 619303-42-3
• Molecular Formula: C₂₃H₃₁N₃O₂
• Molecular Weight: 381.518
• Mol file: 619303-42-3.mol

Synonyms:2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Chemical Property of 2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

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Technology Process of 2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline

There total 1 articles about 2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6,7-dimethoxy-2-[1-(2-nitrobenzyl)-3-piperidyl]-1,2,3,4-tetrahydroisoquinoline dioxalate → 2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (619303-42-3)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; water; at 20 ℃; for 2h;

DOI:10.1248/cpb.51.390

Reference yield: 100.0%

acetic anhydride (108-24-7) + 2-[1-(2-aminobenzyl)-3-piperidyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline (619303-42-3) → 2-{[3-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoquinolinyl)piperidino]methyl}acetanilide

Guidance literature:

With pyridine; at 20 ℃; for 1h;

DOI:10.1248/cpb.51.390