Technology Process of benzyl (1R,3S)-3-tert-butoxycarbonyl-2,2-dimethylcyclobutyl-1-carbamate
There total 4 articles about benzyl (1R,3S)-3-tert-butoxycarbonyl-2,2-dimethylcyclobutyl-1-carbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / tetrahydrofuran / 0 °C
2.1: sodium hypobromide / 1,4-dioxane; water
3.3: Reflux
With
dmap; sodium hypobromide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
tetrahydrofuran; 1,4-dioxane; water;
DOI:10.1007/s00726-011-0912-4
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium periodate; ruthenium trichloride / dichloromethane; water; acetonitrile / 20 °C
2.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine / tetrahydrofuran / 0 °C
3.1: sodium hypobromide / 1,4-dioxane; water
4.3: Reflux
With
dmap; ruthenium trichloride; sodium periodate; sodium hypobromide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine;
In
tetrahydrofuran; 1,4-dioxane; dichloromethane; water; acetonitrile;
DOI:10.1007/s00726-011-0912-4
