Technology Process of 1-(4'-methylbenzyl)-5,6,7-trimethoxyindole
There total 6 articles about 1-(4'-methylbenzyl)-5,6,7-trimethoxyindole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
5,6,7-trimethoxy-1H-indole;
With
potassium iodide; potassium hydroxide;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 0.5h;
4-Methylbenzyl bromide;
In
N,N-dimethyl-formamide;
for 1.5h;
DOI:10.1039/c0ob01038c
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: boron trifluoride-tetrahydrofuran complex / tetrahydrofuran / Reflux
2.1: dipyridinium dichromate / dichloromethane / 20 h / Molecular sieve
3.1: ammonium acetate / acetic acid / 1.5 h / 100 °C
4.1: iron / ethanol; acetic acid / 2 h / 100 °C
5.1: potassium iodide; potassium hydroxide / N,N-dimethyl-formamide / 0.5 h / 20 °C
5.2: 1.5 h
With
dipyridinium dichromate; boron trifluoride-tetrahydrofuran complex; ammonium acetate; iron; potassium iodide; potassium hydroxide;
In
tetrahydrofuran; ethanol; dichloromethane; acetic acid; N,N-dimethyl-formamide;
DOI:10.1039/c0ob01038c
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium hydroxide / methanol / 1 h / Reflux
2.1: boron trifluoride-tetrahydrofuran complex / tetrahydrofuran / Reflux
3.1: dipyridinium dichromate / dichloromethane / 20 h / Molecular sieve
4.1: ammonium acetate / acetic acid / 1.5 h / 100 °C
5.1: iron / ethanol; acetic acid / 2 h / 100 °C
6.1: potassium iodide; potassium hydroxide / N,N-dimethyl-formamide / 0.5 h / 20 °C
6.2: 1.5 h
With
dipyridinium dichromate; boron trifluoride-tetrahydrofuran complex; ammonium acetate; iron; potassium iodide; potassium hydroxide;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; acetic acid; N,N-dimethyl-formamide;
DOI:10.1039/c0ob01038c
