(2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride

Base Information

• Chemical Name: (2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride
• CAS No.: 1189586-09-1
• Molecular Formula: C₁₆H₁₅ClO₂
• Molecular Weight: 274.747
• Mol file: 1189586-09-1.mol

Synonyms:(2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride

Chemical Property of (2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride

There total 1 articles about (2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2,3-dihydrobenzofuran-5-yl)(4-methoxyphenyl)methanol (87901-67-5) → (2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride (1189586-09-1)

Guidance literature:

With thionyl chloride; In dichloromethane;

DOI:10.1021/jo901410b

Reference yield:

piperidine (110-89-4) + (2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride (1189586-09-1) → C21H25NO2*ClH + piperidine hydrochloride (6091-44-7)

Guidance literature:

In water; acetone; at 25 ℃; Concentration; Kinetics;

DOI:10.1021/jo901410b

Reference yield:

(2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride (1189586-09-1) + 3-Trimethylsilylinden (18053-75-3)

Guidance literature:

(2,3-dihydroenzofuran-5-yl)-(4'-methoxyphenyl)-methyl chloride; With gallium(III) trichloride;

3-Trimethylsilylinden; In dichloromethane; at 20 ℃; Kinetics;

DOI:10.1002/anie.201501385

upstream raw materials:

(2,3-dihydrobenzofuran-5-yl)(4-methoxyphenyl)methanol

Downstream raw materials:

piperidine hydrochloride