(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

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Chemical Name:(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione
CAS No.:1280555-52-3
Molecular Formula:C₃₅H₃₃FN₆O₆S
Molecular Weight:684.748
Hs Code.:

Synonyms:(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

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Chemical Property of (S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

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Technology Process of (S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

There total 1 articles about (S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 107089-78-1
3-chloro-4-phenyl 4H-1,2,4-benzothiadiazine 1,1-dioxide

: 198410-25-2
(S)-N-(3-(3-fluoro-4-((N-4-carbobenzoxy)piperazin-1-yl)phenyl)-2-oxo-oxazolidin-5-yl)methylamine

: 1280555-52-3
(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2010.12.028

Reference yield: 91.0%

: 1280555-52-3
(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

: 1280555-59-0
C₂₇H₂₇FN₆O₄S

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 12h;
DOI:10.1016/j.ejmech.2010.12.028

Reference yield:

: 1280555-52-3
(S)-[{N-3-[3-fluoro-4-(4-carbobenzoxypiperazino)phenyl]-2-oxo-5-oxazolidinyl}methyl]amino-4-phenyl-1,4-dihydro-1,2,4-benzothiadiazine 1,1-dione

: 1280555-67-0
C₄₀H₃₄ClFN₆O₆S

Guidance literature:: Multi-step reaction with 2 steps

1: palladium 10% on activated carbon; hydrogen / methanol / 12 h / 20 °C

2: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 12 h / 20 °C

With palladium 10% on activated carbon; hydrogen; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2010.12.028