Methyl 3-amino-4-methyl-5-(4-chlorophenyl)thiophene-2-carboxylate

Base Information

Chemical Name:Methyl 3-amino-4-methyl-5-(4-chlorophenyl)thiophene-2-carboxylate
CAS No.:691394-00-0
Molecular Formula:C₁₃H₁₂ClNO₂S
Molecular Weight:281.763
Hs Code.:
DSSTox Substance ID:DTXSID201167992

Synonyms:METHYL 3-AMINO-4-METHYL-5-(4-CHLOROPHENYL)THIOPHENE-2-CARBOXYLATE;691394-00-0;3-Amino-5-(4-chlorophenyl)-4-methylthiophene-2-carboxylic acid methyl ester;DTXSID201167992;AKOS010565462;Methyl 3-amino-5-(4-chlorophenyl)-4-methyl-2-thiophenecarboxylate

Suppliers and Price of Methyl 3-amino-4-methyl-5-(4-chlorophenyl)thiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Methyl 3-amino-4-methyl-5-(4-chlorophenyl)thiophene-2-carboxylate

Chemical Property:

XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:281.0277275
Heavy Atom Count:18
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(SC(=C1N)C(=O)OC)C2=CC=C(C=C2)Cl

Technology Process of Methyl 3-amino-4-methyl-5-(4-chlorophenyl)thiophene-2-carboxylate

There total 1 articles about Methyl 3-amino-4-methyl-5-(4-chlorophenyl)thiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 106-39-8
bromochlorobenzene

: 85006-31-1
3-amino-4-methyl-2-thiophenecarboxylic acid methyl ester

: 691394-00-0
methyl 3-amino-5-(4-chlorophenyl)-4-methylthiophene-2-carboxylate

Guidance literature:: With PdCl(C₃H₅)(dppb); potassium acetate; In N,N-dimethyl acetamide; at 120 ℃; for 20h; Inert atmosphere;
DOI:10.1016/j.tet.2012.06.053