alpha-D-erythro-Pentofuranosiduronicacid,methyl2,3-dideoxy-3-nitro-(9CI)

Base Information

• Chemical Name: alpha-D-erythro-Pentofuranosiduronicacid,methyl2,3-dideoxy-3-nitro-(9CI)
• CAS No.: 102342-36-9
• Molecular Formula: C₆H₉NO₆
• Molecular Weight: 191.141
• Mol file: 102342-36-9.mol

Synonyms:alpha-D-erythro-Pentofuranosiduronicacid,methyl2,3-dideoxy-3-nitro-(9CI)

Chemical Property of alpha-D-erythro-Pentofuranosiduronicacid,methyl2,3-dideoxy-3-nitro-(9CI)

Chemical Property:

• PSA: 101.58000
• LogP: 0.00090

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of alpha-D-erythro-Pentofuranosiduronicacid,methyl2,3-dideoxy-3-nitro-(9CI)

There total 2 articles about alpha-D-erythro-Pentofuranosiduronicacid,methyl2,3-dideoxy-3-nitro-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

methyl 2,3-dideoxy-3-nitro-α-D-erythro-pentofuranoside (102342-34-7) → methyl 2,3-dideoxy-3-nitro-α-D-erythro-pentofuranosiduronic acid (102342-36-9)

Guidance literature:

With ruthenium(IV) oxide; sodium periodate; In tetrachloromethane; acetonitrile; at 25 ℃; for 4h;

DOI:10.1016/S0040-4039(01)84574-3

Reference yield:

(E/Z)-5-O-Benzoyl-3-deoxy-3-hydroxyimino-1,2-O-isopropylidene-α-D-erythro-pentofuranose (29781-91-7) → methyl 2,3-dideoxy-3-nitro-α-D-erythro-pentofuranosiduronic acid (102342-36-9)

Guidance literature:

Multi-step reaction with 2 steps

2: NaIO₄, RuCl₃*3H₂O / H₂O; CCl₄; acetonitrile / 2 h

With ruthenium trichloride; sodium periodate; In tetrachloromethane; water; acetonitrile;

DOI:10.1021/jo00364a015

upstream raw materials:

methyl 2,3-dideoxy-3-nitro-α-D-erythro-pentofuranoside

(E/Z)-5-O-Benzoyl-3-deoxy-3-hydroxyimino-1,2-O-isopropylidene-α-D-erythro-pentofuranose

Refernces

• 1、 Williams, Theresa M.,Mosher, Harry S.. "A CHIRAL NITRONATE DIANION FROM D-GLYCERALDEHYDE. ENANTIOSPECIFIC SYNTHESIS OF 2,3-DIDEOXY-3-NITRO FURANOSIDES AND PYRANOSIDES". . p. 6269 - 6272. Retrieved 2007/10/02.