C₁₇H₂₀N₂O₃

Base Information

• Chemical Name: C₁₇H₂₀N₂O₃
• CAS No.: 1055233-06-1
• Molecular Formula: C₁₇H₂₀N₂O₃
• Molecular Weight: 300.357
• Mol file: 1055233-06-1.mol

Synonyms:C₁₇H₂₀N₂O₃

Chemical Property of C₁₇H₂₀N₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₂₀N₂O₃

There total 8 articles about C₁₇H₂₀N₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

6-[ethyl-(3-hydroxy-4-isopropylphenyl)amino]nicotinic acid methyl ester (1055233-65-2) → C17H20N2O3 (1055233-06-1)

Guidance literature:

6-[ethyl-(3-hydroxy-4-isopropylphenyl)amino]nicotinic acid methyl ester; With water; sodium hydroxide; In methanol; at 60 ℃; for 0.0833333h;

With hydrogenchloride; water; In methanol;

Reference yield:

5-nitro-2-i-propylphenol (170230-13-4) → C17H20N2O3 (1055233-06-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1.5 h

2.1: hydrogenchloride; hydrogen / palladium on activated charcoal / methanol; water / 1.5 h / 20 °C

3.1: acetic acid / 8 h / 80 °C

3.2: 18 h / 90 °C / Reflux

4.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h

4.2: 2 h

5.1: aluminum (III) chloride / dichloromethane / 7 h / 20 °C / Inert atmosphere

6.1: water; sodium hydroxide / methanol / 0.08 h / 60 °C

With hydrogenchloride; aluminum (III) chloride; water; hydrogen; sodium hydride; potassium carbonate; acetic acid; potassium iodide; sodium hydroxide; palladium on activated charcoal; In methanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

2-isopropyl-5-nitroaniline (132475-93-5) → C17H20N2O3 (1055233-06-1)

Guidance literature:

Multi-step reaction with 7 steps

1.1: sulfuric acid; water; sodium nitrite / 0 - 5 °C

2.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1.5 h

3.1: hydrogenchloride; hydrogen / palladium on activated charcoal / methanol; water / 1.5 h / 20 °C

4.1: acetic acid / 8 h / 80 °C

4.2: 18 h / 90 °C / Reflux

5.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h

5.2: 2 h

6.1: aluminum (III) chloride / dichloromethane / 7 h / 20 °C / Inert atmosphere

7.1: water; sodium hydroxide / methanol / 0.08 h / 60 °C

With hydrogenchloride; aluminum (III) chloride; sulfuric acid; water; hydrogen; sodium hydride; potassium carbonate; acetic acid; potassium iodide; sodium hydroxide; sodium nitrite; palladium on activated charcoal; In methanol; dichloromethane; water; N,N-dimethyl-formamide;

upstream raw materials:

6-[ethyl-(3-hydroxy-4-isopropylphenyl)amino]nicotinic acid methyl ester

5-nitro-2-i-propylphenol

2-isopropyl-5-nitroaniline

C₁₂H₁₇NO₃