6-(Methylsulfanyl)pyridine-3-carbonyl chloride

Base Information

Chemical Name:6-(Methylsulfanyl)pyridine-3-carbonyl chloride
CAS No.:101990-64-1
Molecular Formula:C₇H₆ClNOS
Molecular Weight:187.65
Hs Code.:
DSSTox Substance ID:DTXSID40552513
Wikidata:Q82432819
Mol file:101990-64-1.mol

Synonyms:101990-64-1;6-methylsulfanylpyridine-3-carbonyl chloride;3-Pyridinecarbonyl chloride, 6-(methylthio)- (9CI);6-(Methylsulfanyl)pyridine-3-carbonyl chloride;6-(Methylsulfanyl)nicotinoyl chloride;DTXSID40552513

Suppliers and Price of 6-(Methylsulfanyl)pyridine-3-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 6-(Methylsulfanyl)pyridine-3-carbonyl chloride

Chemical Property:

PSA：55.26000
LogP:2.18250
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:186.9858627
Heavy Atom Count:11
Complexity:153

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CSC1=NC=C(C=C1)C(=O)Cl

Technology Process of 6-(Methylsulfanyl)pyridine-3-carbonyl chloride

There total 1 articles about 6-(Methylsulfanyl)pyridine-3-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 74470-25-0
2-methylthiopyridine-5-carboxylic acid

: 101990-64-1
6-methylsulfanyl-nicotinoyl chloride

Guidance literature:: With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1021/jm050293c

Reference yield:

: 101990-64-1
6-methylsulfanyl-nicotinoyl chloride

: (+/-)-trans-4-[4-cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl-piperazine-1-{N-[6-(methylthio)pyridin-3-yl]}carboxamide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium azide; Et₃N / acetonitrile / 0.67 h / 5 °C

2: toluene / 1.5 h / 100 °C

3: toluene / 0.17 h / 20 °C

With sodium azide; triethylamine; In toluene; acetonitrile; 2: Curtius rearrangement;
DOI:10.1021/jm050293c