2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

Base Information

Chemical Name:2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid
CAS No.:263153-90-8
Molecular Formula:C₄₀H₃₂N₄O₅S₂
Molecular Weight:712.85
Hs Code.:

Synonyms:2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

Suppliers and Price of 2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

There total 4 articles about 2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 263154-23-0
[(Z)-4-Benzothiazol-2-yl-3-methoxymethoxy-benzyloxyimino]-[2-(trityl-amino)-thiazol-4-yl]-acetic acid allyl ester

: 263153-90-8
2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

Guidance literature:: [(Z)-4-Benzothiazol-2-yl-3-methoxymethoxy-benzyloxyimino]-[2-(trityl-amino)-thiazol-4-yl]-acetic acid allyl ester; With tri-n-butyl-tin hydride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; at 20 ℃; for 5h;

With acetic acid; In acetonitrile; at 20 ℃; for 2h; pH=3;
DOI:10.1016/S0968-0896(99)00261-8

Reference yield:

: 56048-54-5
2-(2-hydroxy-4-methylphenyl)benzothiazole

: 263153-90-8
2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

Guidance literature:: Multi-step reaction with 4 steps

1.1: 99 percent / 1,8-diazabicyclo[5.4.0]undec-7-ene / tetrahydrofuran / 0 - 20 °C

2.1: 58 percent / N-bromosuccinimide; 2,2'-azobisisobutyronitrile / CCl₄ / 16 h / Heating; illumination

3.1: 61 percent / K₂CO₃; KI / dimethylformamide / 20 °C

4.1: tributyltin hydride / tetrakis(triphenylphosphine)palladium / tetrahydrofuran / 5 h / 20 °C

4.2: 66 percent / AcOH / acetonitrile / 2 h / 20 °C / pH 3

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; potassium iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; tetrachloromethane; N,N-dimethyl-formamide; 1.1: Etherification / 2.1: Bromination / 3.1: Alkylation / 4.1: deallylation; stannylation / 4.2: Hydrolysis;
DOI:10.1016/S0968-0896(99)00261-8

Reference yield:

: 263153-50-0
2-[2-[(methoxymethyl)oxy]-4-methylphenyl]benzothiazole

: 263153-90-8
2-(tritylamino)-α-[[3-[(methoxymethyl)oxy]-4-(2-benzothiazolyl)benzyloxy]imino]-4-thiazoleacetic acid

Guidance literature:: Multi-step reaction with 3 steps

1.1: 58 percent / N-bromosuccinimide; 2,2'-azobisisobutyronitrile / CCl₄ / 16 h / Heating; illumination

2.1: 61 percent / K₂CO₃; KI / dimethylformamide / 20 °C

3.1: tributyltin hydride / tetrakis(triphenylphosphine)palladium / tetrahydrofuran / 5 h / 20 °C

3.2: 66 percent / AcOH / acetonitrile / 2 h / 20 °C / pH 3

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; potassium carbonate; potassium iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; tetrachloromethane; N,N-dimethyl-formamide; 1.1: Bromination / 2.1: Alkylation / 3.1: deallylation; stannylation / 3.2: Hydrolysis;
DOI:10.1016/S0968-0896(99)00261-8