(R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N₅-[amino-(nitroimino)methyl]-N₂-(diphenylacetyl)-ornithinamide

Base Information

• Chemical Name: (R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N₅-[amino-(nitroimino)methyl]-N₂-(diphenylacetyl)-ornithinamide
• CAS No.: 191868-20-9
• Molecular Formula: C₂₉H₃₃N₇O₅
• Molecular Weight: 559.625

Synonyms:(R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N₅-[amino-(nitroimino)methyl]-N₂-(diphenylacetyl)-ornithinamide

Chemical Property of (R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N₅-[amino-(nitroimino)methyl]-N₂-(diphenylacetyl)-ornithinamide

Chemical Property:

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Technology Process of (R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N₅-[amino-(nitroimino)methyl]-N₂-(diphenylacetyl)-ornithinamide

There total 5 articles about (R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N₅-[amino-(nitroimino)methyl]-N₂-(diphenylacetyl)-ornithinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(R)-N5-[amino-(nitroimino)-methyl]-N2-(diphenylacetyl)ornithine (159013-58-8) + 2-[4-(aminomethyl)phenyl]acetamide (181466-81-9) → (R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N5-[amino-(nitroimino)methyl]-N2-(diphenylacetyl)-ornithinamide (191868-20-9)

Guidance literature:

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N-methyl-acetamide;

Reference yield: 73.0%

→ (R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N5-[amino-(nitroimino)methyl]-N2-(diphenylacetyl)-ornithinamide (191868-20-9)

Guidance literature:

Reference yield:

2-(4-cyanophenyl)acetamide (117753-06-7) → (R)-N-[[4-(Aminocarbonylmethyl)phenyl)methyl]-N5-[amino-(nitroimino)methyl]-N2-(diphenylacetyl)-ornithinamide (191868-20-9)

Guidance literature:

Multi-step reaction with 2 steps

1: aluminum nickel / methanol; hydrogen

2: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate / N-methyl-acetamide

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; aluminum nickel; In N-methyl-acetamide; methanol; hydrogen;

upstream raw materials:

(R)-N₅-[amino-(nitroimino)-methyl]-N₂-(diphenylacetyl)ornithine

2-[4-(aminomethyl)phenyl]acetamide

diphenylacetic acid chloride

4-cyanophenylacetic acid

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