3'-NITRO-BIPHENYL-4-SULFONYL CHLORIDE

Base Information

• Chemical Name: 3'-NITRO-BIPHENYL-4-SULFONYL CHLORIDE
• CAS No.: 101366-50-1
• Molecular Formula: C12H8 Cl N O4 S
• Molecular Weight: 297.71422
• Mol file: 101366-50-1.mol

Synonyms:3’-NITRO-BIPHENYL-4-SULFONYL CHLORIDE

Chemical Property of 3'-NITRO-BIPHENYL-4-SULFONYL CHLORIDE

Chemical Property:

• Boiling Point: 446.8±38.0 °C(Predicted)
• PSA: 88.34000
• Density: 1.464±0.06 g/cm3(Predicted)
• LogP: 4.79330

Purity/Quality:

98%min ^*data from raw suppliers

3'-NITRO-BIPHENYL-4-SULFONYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3'-NITRO-BIPHENYL-4-SULFONYL CHLORIDE

There total 2 articles about 3'-NITRO-BIPHENYL-4-SULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

3'-nitrobiphenyl-4-sulfonic acid (918638-37-6) → 3'-nitrobiphenyl-4-sulfonyl chloride (101366-50-1)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; for 4h; Heating;

DOI:10.1021/jm051236m

Reference yield: 65.0%

3-nitro-1,1'-biphenyl (2113-58-8) → 3'-nitrobiphenyl-4-sulfonyl chloride (101366-50-1)

Guidance literature:

With chlorosulfonic acid; at 20 ℃; for 1h;

DOI:10.1021/jm010861y

Reference yield: 62.0%

benzoxazole (273-53-0,29791-96-6) + 3'-nitrobiphenyl-4-sulfonyl chloride (101366-50-1) → 2-(3-nitrophenyl)benzoxazole (840-56-2)

Guidance literature:

With copper(l) iodide; oxygen; palladium diacetate; potassium carbonate; In 1,4-dioxane; at 120 ℃; for 48h; Sealed tube;

DOI:10.1039/c1cc14718h

upstream raw materials:

3-nitro-1,1'-biphenyl

3'-nitrobiphenyl-4-sulfonic acid

Downstream raw materials:

3'-nitro-biphenyl-4-sulfonic acid (2-phenyl-2H-pyrazol-3-yl)-amide

3'-nitro-biphenyl-4-sulfonic acid (3-hydroxy-propyl)-(2-phenyl-2H-pyrazol-3-yl)-amide

2-(3-nitrophenyl)benzoxazole

Refernces

• 1、 -. "ARYL ALKYL SULFONAMIDES AS THERAPEUTIC AGENTS FOR THE TREATMENT OF BONE CONDITIONS". Page/Page column 102. . Retrieved 2008/06/13.