N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine

Base Information

Chemical Name:N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine
CAS No.:1360593-79-8
Molecular Formula:C₁₆H₂₄N₄O₅S
Molecular Weight:384.456
Hs Code.:

Synonyms:N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine

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Technology Process of N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine

There total 2 articles about N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1360593-51-6
1-[((N,N-dimethylsulfamoyl)-4,5-dimethoxyphenyl)acetyl]-4-propylthiosemicarbazide

: 1360593-79-8
N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine

Guidance literature:: With iodine; potassium iodide; sodium hydroxide; In ethanol; at 0 - 20 ℃; pH=9;
DOI:10.1016/j.bmc.2011.12.031

Reference yield:

: 1016637-96-9
2-(2-hydrazinyl-2-oxoethyl)-N,N-dimethyl-4,5-dimethoxybenzenesulfonamide

: 1360593-79-8
N-{5-[2-(N,N-dimethylsulfamoyl)-4,5-dimethoxybenzyl]-1,3,4-oxadiazol-2-yl}-N-propylamine

Guidance literature:: Multi-step reaction with 2 steps

1: ethanol / 1 h / Reflux

2: iodine; potassium iodide; sodium hydroxide / ethanol / 0 - 20 °C / pH 9

With iodine; potassium iodide; sodium hydroxide; In ethanol;
DOI:10.1016/j.bmc.2011.12.031