5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

Base Information

Chemical Name:5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester
CAS No.:1011476-59-7
Molecular Formula:C₂₀H₂₅N₃O₃
Molecular Weight:355.437
Hs Code.:

Synonyms:5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

Suppliers and Price of 5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

There total 5 articles about 5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 910635-33-5
3-ethyl-N,4-dihydroxy-5-methylbenzimidamide

: 1011476-30-4
5,6-diethyl-nicotinic acid hydrochloride

: 1011476-59-7
5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

Guidance literature:: 5,6-diethyl-nicotinic acid hydrochloride; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.0833333h;

3-ethyl-N,4-dihydroxy-5-methylbenzimidamide; In dichloromethane; at 20 ℃; for 0.5h;

Reference yield:

: 1011476-33-7
5,6-diethyl-nicotinic acid tert-butyl ester

: 1011476-30-4
5,6-diethyl-nicotinic acid hydrochloride

: 1011476-59-7
5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

Guidance literature:: 5,6-diethyl-nicotinic acid hydrochloride; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 0.0833333h;

5,6-diethyl-nicotinic acid tert-butyl ester; In dichloromethane; for 0.5h;

Reference yield:

: 1011476-31-5
5-chloro-6-vinyl-nicotinic acid tert.-butyl ester

: 1011476-59-7
5,6-diethyl-nicotinic acid (3-ethyl-4,N-dihydroxy-5-methyl-benzamidine) ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: caesium carbonate / tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri-tert-butyl phosphine / 1,4-dioxane / 15 h / 100 °C

2.1: hydrogen / palladium 10% on activated carbon / tetrahydrofuran; methanol / 3 h / 20 °C / 760.05 Torr

3.1: hydrogenchloride; water / 3 h / 65 °C

4.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.08 h / 20 °C

4.2: 0.5 h / 20 °C

With hydrogenchloride; water; hydrogen; caesium carbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri-tert-butyl phosphine; palladium 10% on activated carbon; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane;