2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine

Base Information

Chemical Name:2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine
CAS No.:1609980-53-1
Molecular Formula:C₁₆H₁₄ClF₃N₄O
Molecular Weight:370.762
Hs Code.:

Synonyms:2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine

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Chemical Property of 2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine

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Technology Process of 2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine

There total 3 articles about 2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 367-57-7
1,1,1-Trifluoro-2,4-pentanedione

: 1609980-54-2
3-[3-(4-chlorophenoxy)propyl]-1H-1,2,4-triazol-5-amine

: 1609980-53-1
2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: With acetic acid; at 135 ℃; for 15h;

Reference yield:

: 106-48-9,82344-39-6
4-chloro-phenol

: 1609980-53-1
2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2: pyridine / 42 h / 125 °C

3: acetic acid / 15 h / 135 °C

With pyridine; potassium carbonate; acetic acid; In N,N-dimethyl-formamide;

Reference yield:

: 209052-80-2
methyl 4-(4-chlorophenoxy)butanoate

: 1609980-53-1
2-[3-(4-chlorophenoxy)propyl]-5-methyl-7-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 42 h / 125 °C

2: acetic acid / 15 h / 135 °C

With pyridine; acetic acid;