(3R,3aS,6aR)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate

Base Information

Chemical Name:(3R,3aS,6aR)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate
CAS No.:1426302-88-6
Molecular Formula:C₂₁H₁₈O₄
Molecular Weight:334.372
Hs Code.:

Synonyms:(3R,3aS,6aR)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3R,3aS,6aR)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate

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Technology Process of (3R,3aS,6aR)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate

There total 1 articles about (3R,3aS,6aR)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 117-34-0
2,2-diphenylacetic acid

: 139367-24-1,139491-15-9,141554-44-1,148555-09-3,148555-10-6
(3R,3aR,6aR)-3-hydroxy-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-2-one

: 1426302-88-6
(3R,3aS,6aR)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate

: (3S,3aR,6aS)-3,3a,4,6a-tetrahydro-2-oxo-2H-cyclopenta[b]furan-3-yl 2,2-diphenylacetate

: 157968-47-3
(+)-(3S,3aS,6aS)-3-hydroxy-3,3a,6,6a-tetrahydro-cyclopenta[b]furan-2-one

Guidance literature:: With (R)-(+)-2-phenyl-2,3-dihydrobenzo[d]imidazo[2,1-b]thiazole; 2,2-dimethylpropanoic anhydride; N-ethyl-N,N-diisopropylamine; In diethyl ether; at 20 ℃; for 12h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ol303453j