benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

Base Information

• Chemical Name: benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate
• CAS No.: 113457-86-6
• Molecular Formula: C₄₅H₄₀N₄O₇
• Molecular Weight: 748.835
• Mol file: 113457-86-6.mol

Synonyms:benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

Chemical Property of benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

There total 4 articles about benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

benzyl 4-benzyloxy-3-<(4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate (113457-85-5) → benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate (113457-86-6)

Guidance literature:

With sodium cyanoborohydride; In acetic acid; for 1h; Ambient temperature;

Reference yield:

4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylic acid (113457-84-4) → benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate (113457-86-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 73 percent / CMC / CH₂Cl₂; dimethylformamide / Ambient temperature

2: 74 percent / sodium cyanoborohydride / acetic acid / 1 h / Ambient temperature

With sodium cyanoborohydride; In dichloromethane; acetic acid; N,N-dimethyl-formamide;

Reference yield:

methyl 4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate (102357-93-7) → benzyl 4-benzyloxy-3-<(4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate (113457-86-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 93 percent / KOH / H₂O; methanol / 1 h / Heating

2: 73 percent / CMC / CH₂Cl₂; dimethylformamide / Ambient temperature

3: 74 percent / sodium cyanoborohydride / acetic acid / 1 h / Ambient temperature

With potassium hydroxide; sodium cyanoborohydride; In methanol; dichloromethane; water; acetic acid; N,N-dimethyl-formamide;

upstream raw materials:

benzyl 4-benzyloxy-3-<(4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylic acid

methyl 4-benzyloxy-3,6-dihydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

benzyl 4-benzyloxy-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

Downstream raw materials:

benzyl 4-benzyloxy-3-<(4-benzyloxy-3-carbamoyl-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indol-7-yl)carbonyl>-1,2,3,6-tetrahydro-5-methoxypyrrolo<3,2-e>indole-7-carboxylate

6-(6-Carbamoyl-5-hydroxy-4-methoxy-3,6,7,8-tetrahydro-pyrrolo[3,2-e]indole-2-carbonyl)-5-hydroxy-4-methoxy-3,6,7,8-tetrahydro-pyrrolo[3,2-e]indole-2-carboxylic acid