7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

Base Information

Chemical Name:7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime
CAS No.:827585-06-8
Molecular Formula:C₃₀H₃₉N₅O₃
Molecular Weight:517.671
Hs Code.:

7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one <i>O</i>-(3,4-dimethoxy-benzyl)-oxime

Synonyms:7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

Suppliers and Price of 7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

There total 10 articles about 7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 7-((E)-5-Adamantan-1-yl-3-methyl-pent-2-enyl)-9-(2-cyano-ethyl)-6-[(Z)-3,4-dimethoxy-benzyloxyimino]-6,9-dihydro-1H-purin-7-ium; bromide

: 827585-06-8
7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

Guidance literature:: With potassium carbonate; In methanol; at 20 ℃; for 1h;
DOI:10.1021/jo048622g

Reference yield:

: 773-37-5
1-(2-bromo-ethyl)-adamantane

: 827585-06-8
7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

Guidance literature:: Multi-step reaction with 6 steps

1.1: butyllithium / tetrahydrofuran; hexane / -45 - 20 °C

1.2: 56 percent / tetrahydrofuran; hexane / 1.33 h

2.1: 95 percent / DDQ / acetonitrile; H₂O / 1.5 h / 20 °C

3.1: 97 percent / tetrahydrofuran / 0.33 h / 0 °C

4.1: 80 percent / aq. HBr / petroleum ether / 1 h / 0 °C

5.1: 47 percent / dimethylformamide / 72 h / 45 °C

6.1: 73 percent / K₂CO₃ / methanol / 1 h / 20 °C

With n-butyllithium; hydrogen bromide; potassium carbonate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; methanol; hexane; water; N,N-dimethyl-formamide; acetonitrile; Petroleum ether;
DOI:10.1021/jo048622g

Reference yield:

: 6053-96-9
O-3,4-dimethyloxybenzyl-hydroxylamine

: 827585-06-8
7-(5-adamantan-1-yl-3-methyl-pent-2-enyl)-1,7-dihydro-purin-6-one O-(3,4-dimethoxy-benzyl)-oxime

Guidance literature:: Multi-step reaction with 3 steps

1: 59 percent / diisopropylethylamine / ethanol / 24 h / Heating

2: 47 percent / dimethylformamide / 72 h / 45 °C

3: 73 percent / K₂CO₃ / methanol / 1 h / 20 °C

With potassium carbonate; N-ethyl-N,N-diisopropylamine; In methanol; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jo048622g