(2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran

Base Information

Chemical Name:(2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran
CAS No.:1094853-95-8
Molecular Formula:C₂₆H₂₈O₅S
Molecular Weight:452.571
Hs Code.:

Synonyms:(2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran

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Technology Process of (2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran

There total 1 articles about (2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1094854-07-5
lactol

: 618-41-7
Benzenesulfinic acid

: 1094853-95-8
(2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran

Guidance literature:: With camphor-10-sulfonic acid; calcium chloride; In dichloromethane; at 25 ℃; for 4h;
DOI:10.1021/ol8024617

Reference yield: 52.0%

: 1094853-95-8
(2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran

: [4-(benzyloxy)-3-methoxyphenyl]magnesium bromide

: (7S,7'R,8R,8'R)-4,4'-dibenzyloxy-3,3'-dimethoxy-7,7'-epoxylignane

: 1094853-94-7
C₃₄H₃₆O₅

Guidance literature:: [4-(benzyloxy)-3-methoxyphenyl]magnesium bromide; With zinc dibromide; In tetrahydrofuran; at 25 ℃;

(2S,3R,4R)-2-(4-(benzyloxy)-3-methoxyphenyl)-3,4-dimethyl-5-(phenylsulfonyl)tetrahydrofuran; In tetrahydrofuran; at 0 - 25 ℃; optical yield given as %de; diastereoselective reaction;
DOI:10.1021/ol8024617