Chemical Property of ATRACTYLOSIDE SODIUM SALT
Chemical Property:
- PSA：272.14000
- LogP:3.14340
- Purity/Quality:
-
98%min *data from raw suppliers
Atractyloside sodium salt *data from reagent suppliers
Safty Information:
- Pictogram(s):
T
- Hazard Codes:T
- Statements:
23/24/25
- Safety Statements:
36/37/39-45
- MSDS Files:
-
SDS file from LookChem
Useful:
-
Uses
A specific inhibitor of the adenine nucleotide translocase (ANT), which is a mitochondrial ADP/ATP carrier. It is also a proapoptotic ligand of ANT that induces pore formation by ANT, and results in p ermeabilization of the mitochondria membrane. Studies on rat hearts suggest that Atractyloside inhibits chloride channels from the mitochondrial membrane. It is used to probe the source of procaspase 8 in human fibroblasts and mouse clonal striatal cells, as related to death receptor-mediated apoptosis. ATRACTYLOSIDE SODIUM SALT induces the release of ahyaluronidase-induced murine WW domain-containing oxidore ductase from cultured COS-7 cells, with respect to tumor necrosis factor cytotoxicity.
