9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde

Base Information

• Chemical Name: 9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde
• CAS No.: 1331876-93-7
• Molecular Formula: C₂₉H₁₄F₈O₂
• Molecular Weight: 546.416
• Mol file: 1331876-93-7.mol

Synonyms:9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde

Chemical Property of 9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde

There total 1 articles about 9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,7-dibromo-9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene (879291-99-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde (1331876-93-7)

Guidance literature:

2,7-dibromo-9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 2h;

N,N-dimethyl-formamide; In tetrahydrofuran; hexane; at -78 - 20 ℃;

DOI:10.1002/pola.24828

Reference yield:

9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde (1331876-93-7) → C29H18F8O2

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1002/pola.24828

Reference yield:

9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene-2,7-dicarbaldehyde (1331876-93-7) → 2,7-bis(diethoxyphosphorylmethyl)-9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene (1331876-95-9)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 20 °C

2: carbon tetrabromide; triphenylphosphine / tetrahydrofuran / 1 h / 20 °C

3: 15 h / 150 °C

With lithium aluminium tetrahydride; carbon tetrabromide; triphenylphosphine; In tetrahydrofuran;

DOI:10.1002/pola.24828

upstream raw materials:

2,7-dibromo-9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene

N,N-dimethyl-formamide

Downstream raw materials:

2,7-bis(diethoxyphosphorylmethyl)-9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene

2,7-bis(bromomethyl)-9,9-bis(4-fluoro-3-(trifluoromethyl)phenyl)fluorene