5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin

Base Information

• Chemical Name: 5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin
• CAS No.: 130317-56-5
• Molecular Formula: C₁₉H₁₇N₃O₂
• Molecular Weight: 319.363
• Mol file: 130317-56-5.mol

Synonyms:5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin

Chemical Property of 5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin

There total 3 articles about 5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

5,7-Diphenyl-2,3,4,5,6,7-Hexahydro-8-nitro-1H-imidazo<1,2-a>pyridin-5-ol → 5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin (130317-56-5)

Guidance literature:

With hydrogenchloride; In ethanol; Heating;

DOI:10.1002/ardp.19933260606

Reference yield: 55.1%

2-(nitromethylene)imidazolidine (13623-98-8) + benzalacetophenone (94-41-7) → 5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin (130317-56-5)

Guidance literature:

With hydrogenchloride; In acetonitrile; for 6h; Heating;

DOI:10.1246/bcsj.63.1921

Reference yield:

1,3-diphenyl-propen-3-one (614-47-1) → 5,7-Diphenyl-8-nitro-2,3,4,7-tetrahydro-1H-imidazo<1,2-a>pyridin (130317-56-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 57 percent / ethanol / 8 h / Heating

2: 57 percent / 5percent aq. HCl / ethanol / Heating

With hydrogenchloride; In ethanol;

DOI:10.1002/ardp.19933260606

upstream raw materials:

2-(nitromethylene)imidazolidine

benzalacetophenone

1,3-diphenyl-propen-3-one