1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose

Base Information

• Chemical Name: 1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose
• CAS No.: 67279-09-8
• Molecular Formula: C₁₇H₁₇F₃N₂O₈
• Molecular Weight: 434.326
• Mol file: 67279-09-8.mol

Synonyms:1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose

Chemical Property of 1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose

There total 5 articles about 1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

acetic anhydride (108-24-7) + 2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α,β-L-xylo-hexopyranose (76753-25-8,76753-31-6,76753-32-7,76760-23-1,81312-34-7,81312-35-8) → 1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose (67279-09-8)

Guidance literature:

With pyridine; at 25 ℃; for 20h;

DOI:10.1016/S0008-6215(00)84673-X

Reference yield:

methyl-2,3,6-tridesoxy-3-trifluoroacetamido-β-L-xylo-hexopyranoside (72002-53-0) → 1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose (67279-09-8)

Guidance literature:

Multi-step reaction with 3 steps

1: 96 percent / pyridine / 3 h / 0 °C

2: 86 percent / acetic acid / H₂O / 1.25 h / Heating

3: 80 percent / pyridine / 20 h / 25 °C

With pyridine; acetic acid; In water;

DOI:10.1016/S0008-6215(00)84673-X

Reference yield:

methyl-3-amino-2,3,6-tridesoxy-β-L-xylo-hexopyranoside (67737-60-4) → 1-O-acetyl-2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranose (67279-09-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 48 percent / CH₂Cl₂ / 3 h / 20 °C

2: 96 percent / pyridine / 3 h / 0 °C

3: 86 percent / acetic acid / H₂O / 1.25 h / Heating

4: 80 percent / pyridine / 20 h / 25 °C

With pyridine; acetic acid; In dichloromethane; water;

DOI:10.1016/S0008-6215(00)84673-X

upstream raw materials:

acetic anhydride

2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α,β-L-xylo-hexopyranose

methyl-3-amino-2,3,6-tridesoxy-β-L-xylo-hexopyranoside

methyl-2,3,6-tridesoxy-3-trifluoroacetamido-β-L-xylo-hexopyranoside

Downstream raw materials:

7-O-(2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-L-xylo-hexopyranosyl)daunomycinone